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Index > Protein center > CRLF2(Gene name) > Human
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  • CRLF2 (Gene name),
  • Cytokine receptor-like factor 2 (Protein name ),  CRLF2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CRLF2(CRL2;ILXR;TSLPR);
    Protein name:
    Cytokine receptor-like factor 2;
    Alternative:
    IL-XR;Cytokine receptor-like 2;Thymic stromal lymphopoietin protein receptor(TSLP receptor);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of CRLF2 and IL7R.
    Function:
    Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system.
    Subcellular Location:
    Isoform 2 Secreted
    Protein Attributes:
    Sequence length:
    371
    Sequence:
    50:
    MGRLVLLWGA | AVFLLGGWMA | LGQGGAAEGV | QIQIIYFNLE | TVQVTWNASK | 
    100:
    YSRTNLTFHY | RFNGDEAYDQ | CTNYLLQEGH | TSGCLLDAEQ | RDDILYFSIR | 
    150:
    NGTHPVFTAS | RWMVYYLKPS | SPKHVRFSWH | QDAVTVTCSD | LSYGDLLYEV | 
    200:
    QYRSPFDTEW | QSKQENTCNV | TIEGLDAEKC | YSFWVRVKAM | EDVYGPDTYP | 
    250:
    SDWSEVTCWQ | RGEIRDACAE | TPTPPKPKLS | KFILISSLAI | LLMVSLLLLS | 
    300:
    LWKLWRVKKF | LIPSVPDPKS | IFPGLFEIHQ | GNFQEWITDT | QNVAHLHKMA | 
    350:
    GAEQESGPEE | PLVVQLAKTE | AESPRMLDPQ | TEEKEASGGS | LQLPHQPLQG | 
    371:
    GDVVTIGGFT | FVMNDRSYVA | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cytokine receptor-like factor 2
    Cat.:
    E11720r
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Cytokine receptor-like factor 2
    Cat.:
    E11720m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Cytokine receptor-like factor 2
    Cat.:
    E11720h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Cytokine receptor-like factor 2
    Cat.:
    U11720r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cytokine receptor-like factor 2
    Cat.:
    U11720h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Cytokine receptor-like factor 2
    Cat.:
    U11720m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Cytokine receptor-like factor 2
    Cat.:
    P11720Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cytokine receptor-like factor 2
    Cat.:
    P11720Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Cytokine receptor-like factor 2
    Cat.:
    P11720Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Cytokine receptor-like factor 2
    Monoclonal Antibody for Human Cytokine receptor-like factor 2
    Monoclonal Antibody for Human Cytokine receptor-like factor 2
    Protein for Human Cytokine receptor-like factor 2
    Protein for Human Cytokine receptor-like factor 2
    Protein for Human Cytokine receptor-like factor 2

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    References
    1. 1.
      "Identification of a novel type I cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes."
      Zhang W. , Wang J. , Wang Q. , Chen G. , Zhang J. , Chen T. , Wan T. , Zhang Y. , Cao X.
      Biochem. Biophys. Res. Commun.281:878-883(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Dendritic cell.
    2. 2.
      "Molecular cloning of a human novel type I cytokine receptor related to delta1/TSLPR."
      Tonozuka Y. , Fujio K. , Sugiyama T. , Nosaka T. , Hirai M. , Kitamura T.
      Cytogenet. Cell Genet.93:23-25(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: T-cell.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION AS A RECEPTOR FOR TSLP
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Lung.
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